![Sample our Medicine, Dentistry, Nursing & Allied Health journals, sign in here to start your FREE access for 14 days]({"type":"image" , "src" : "/sda/5944/TOC-Subject-Sample-2021-Medicine-Dentistry-Nursing-Allied-Health.jpg"})
Abstract
The fruitless (fru) gene in Drosophila plays a pivotal role in the formation of neural circuits underlying gender-specific behaviors. Specific labeling of fru-expressing neurons has revealed a core circuit responsible for male courtship behavior. Females with a small number of masculinized neuronal clusters in their brain can initiate male-type courtship behavior. By examining the correlations between the masculinized neurons and behavioral gender type, a male-specific neuronal cluster, named P1, which coexpresses fru and doublesex, was identified as a putative trigger center for male-type courtship behavior. P1 neurons extend dendrite to the lateral horn, where multimodal sensory inputs converge. Molecular studies suggest that fru determines the level of masculinization of neurons by orchestrating the transcription of a set of downstream genes, which remain to be identified.
| Abbreviations | ||
| MOL | = | the muscle of Lawrence |
| INAH3 | = | interstitial nucleus of anterior hypothalamus 3 |
| mAL | = | medially located just above the antennal lobe |
| MARCM | = | mosaic analysis with a repressible cell marker |
| LH | = | lateral horn |
| PN | = | projection neuron |
| Grs | = | gustatory receptors |
| iACT | = | inner antennocerebral tract |
| mACT | = | middle antennocerebral tract. |
| Abbreviations | ||
| MOL | = | the muscle of Lawrence |
| INAH3 | = | interstitial nucleus of anterior hypothalamus 3 |
| mAL | = | medially located just above the antennal lobe |
| MARCM | = | mosaic analysis with a repressible cell marker |
| LH | = | lateral horn |
| PN | = | projection neuron |
| Grs | = | gustatory receptors |
| iACT | = | inner antennocerebral tract |
| mACT | = | middle antennocerebral tract. |