Article Title: Histological and Biochemical Evaluation of the Effects of Silver Nanoparticles (AgNPs) Versus Titanium Dioxide Nanoparticles (TiO2NPs) on Rat Parotid Gland
Authors: Sara M. Abdel Aal, Maha Z. Mohammed, Abeer A. Abdelrahman, Walaa Samy, Ghadeer M. M. Abdelaal, Raghda H. Deraz, and Shaimaa A. Abdelrahman
Journal: Ultrastructural Pathology
Bibliometrics: Volume 47, Number 4, Pages 339-363
DOI: http://dx.doi.org/10.1080/01913123.2023.2205924
This article was published with the incorrect figure legends, which have been corrected and re-published online.
Incorrect legends
Figure 1. A photomicrograph of H & E-stained sections of control group showing. A: normal general architecture of parotid gland; closely packed serous acini (a), separated by thin septa (arrow) and excretory ducts (d) (H&E, x100, Scale bar; 50 μm). B: The lobule consists of closely packed purely serous acini (a) lined by cells with eosinophilic granular cytoplasm and basal rounded nuclei and intralobular duct system of intercalated (*) and striated (d) ducts and blood vessels (arrow heads) are seen. (H&E, x 400; scale bar 20 μm). Mallory trichrome stained sections of the same group showing C: Few collagen fibers (arrows) between the lobules, around interlobular ducts and blood vessels. (Mallory trichrome, x200, Scale bar; 30 μm). Weak positive cytoplasmic immunoreaction for CD68 in few inter-acinar cells (arrow) (CD-68 immune-staining ×400, Scale bar 20 μm). D: Caspase 3 immunostained sections showing weak positive cytoplasmic immunoreaction for caspase-3 in few cells (arrows) (Immunoperoxidase reaction for caspase3 ×400, Scale bar; 20 μm)
Figure 2. A photomicrograph of H & E stained sections of from AgNPs injected group showing A&B: Disorganized lobules with separated acini (a) which appeared widely separated in some sections as in (b)with irregular outlines, separated by wide CT septa (s) These septa have dilated congested blood vessel (bV), inflammatory infiltration (IF), and excretory duct (d) which appeared dilated in some areas as in(b) Note: homogenous acidophilic area (*) in(b). C: Thick septa with extensive collagen fibers (thick arrow),dilated ducts (d) multiple adipocytes (Ad) are seen in some sections (H&E, x100, Scale bar; 50 μm).D: Showing most of the acini (a) with irregular outlines (curved arrow) and are widely separated. Some acinar cells contain small darkly stained nuclei (arrowhead). connective tissue septa in between the lobes with inflammatory infiltration (IF), congested blood vessels (bv) and ducts(d) are also seen. (H&E, x400; scale bar 20 μm). E: Extensive collagen fibers in Ag-Nps injected group (arrows) in between the lobules, around interlobular ducts and blood vessels (Mallory trichrome, x200, Scale bar; 30 μm). F: Strong positive CD-68 cytoplasmic immunoreaction in many cells between acini (arrows) (CD-68 immune-staining ×400, Scale bar 20μm). G: Strong positive immunoreaction for caspase 3 in the cytoplasm of most acinar cells (arrows) (Immunoperoxidase reaction for caspase3 ×400, Scale bar; 20μm)
Figure 3. A photomicrograph of H & E stained sections of from AgNPs injected group showing A&B: Disorganized lobules with separated acini (a) which appeared widely separated in some sections as in (b)with irregular outlines, separated by wide CT septa (s) These septa have dilated congested blood vessel (bV), inflammatory infiltration (IF), and excretory duct (d) which appeared dilated in some areas as in(b) Note: homogenous acidophilic area (*) in(b) .C: Thick septa with extensive collagen fibers (thick arrow),dilated ducts (d) multiple adipocytes (Ad) are seen in some sections (H&E, x 100, Scale bar; 50 μm).D: Showing most of the acini (a) with irregular outlines (curved arrow) and are widely separated. Some acinar cells contain small darkly stained nuclei (arrowhead). connective tissue septa in between the lobes with inflammatory infiltration (IF), congested blood vessels (bv) and ducts(d) are also seen. (H&E, x 400; scale bar 20 μm). E: Extensive collagen fibers in Ag-Nps injected group (arrows) in between the lobules, around interlobular ducts and blood vessels (Mallory trichrome, x200, Scale bar; 30 μm). F: Strong positive CD-68 cytoplasmic immunoreaction in many cells between acini (arrows) (CD-68 immune-staining ×400, Scale bar 20μm). G: Strong positive immunoreaction for caspase 3 in the cytoplasm of most acinar cells (arrows) (Immunoperoxidase reaction for caspase3 ×400, Scale bar; 20μm).
Correct legends
Figure 1. Electron micrographs showing (A): AgNps and (B): TiO2NPs less than 100 nm diameter (TEM, Scale bar 200 nm).
Figure 2: A photomicrograph of H & E-stained sections of control group showing. A: normal general architecture of parotid gland; closely packed serous acini (a), separated by thin septa (arrow) and excretory ducts (d) (H&E, x 100, Scale bar; 50 μm). B: The lobule consists of closely packed purely serous acini (a) lined by cells with eosinophilic granular cytoplasm and basal rounded nuclei and intralobular duct system of intercalated (*) and striated (d) ducts and blood vessels (arrow heads) are seen. (H&E, x 400; scale bar 20 μm). Mallory trichrome stained sections of the same group showing C: Few collagen fibers (arrows) between the lobules, around interlobular ducts and blood vessels. (Mallory trichrome, x200, Scale bar; 30 μm). Weak positive cytoplasmic immunoreaction for CD-68 in few inter-acinar cells (arrow) (CD-68 immune-staining ×400, Scale bar 20μm). D: Caspase 3 immunostained sections showing weak positive cytoplasmic immunoreaction for caspase-3 in few cells (arrows) (Immunoperoxidase reaction for caspase3 ×400, Scale bar; 20μm).
Figure 3: A photomicrograph of H & E stained sections of AgNPs injected group showing A&B: Disorganized lobules with separated acini (a) which appeared widely separated in some sections as in (b)with irregular outlines, separated by wide CT septa (s) These septa have dilated congested blood vessel (bV), inflammatory infiltration (IF), and excretory duct (d) which appeared dilated in some areas as in(b) Note: homogenous acidophilic area (*) in(b) .C: Thick septa with extensive collagen fibers (thick arrow),dilated ducts (d) multiple adipocytes (Ad) are seen in some sections (H&E, x 100, Scale bar; 50 μm).D: Showing most of the acini (a) with irregular outlines (curved arrow) and are widely separated. Some acinar cells contain small darkly stained nuclei (arrowhead). connective tissue septa in between the lobes with inflammatory infiltration (IF), congested blood vessels (bv) and ducts(d) are also seen. (H&E, x 400; scale bar 20 μm). E: Extensive collagen fibers in Ag-Nps injected group (arrows) in between the lobules, around interlobular ducts and blood vessels (Mallory trichrome, x200, Scale bar; 30 μm). F: Strong positive CD-68 cytoplasmic immunoreaction in many cells between acini (arrows) (CD-68 immune-staining ×400, Scale bar 20μm). G: Strong positive immunoreaction for caspase 3 in the cytoplasm of most acinar cells (arrows) (Immunoperoxidase reaction for caspase3 ×400, Scale bar; 20μm).