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ABSTRACT
The rapid spread of SARS-CoV-2 caused a global pandemic. Due to the lack of treatment and vaccines, safety strategies must be found to stop the virus dissemination. The objective of this study was to evaluate the virucidal activity of ozonated water, a powerful oxidizing agent, against SARS-CoV-2. A special faucet was the source of ozonated water at a low concentration (0.2–0.8 ppm). At this concentration, tests with SARS-Cov-2 in Vero CCL81 lineage showed two log10 reduction in virus infectivity upon 1 min exposure to ozonated water, in comparison to controls. It shows the potential as an efficient and rapid alternative for controlling viral spread in hospitals and other environments.
Acknowledgments
MHC would like to thank the Coordenação de Aperfeiçoamento de Pessoal de Nível Superior – Brazil (CAPES) – Financial Code 001, and MTGA the National Council for Scientific and Technological Development – CNPq Brazil, for the scholarships granted.
EA thanks the National Research Council (CNPq) (grant number 403201/2020-9) and the State of Sao Paulo Research Foundation (FAPESP) (grant number 2018/25605-6). We are grateful to Dr. Edison L. Durigon (Institute of Biomedical Science, University of São Paulo, Brazil) for sharing the initial SARS CoV-2 clinical isolate.
Disclosure statement
The authors declare no conflicts of interest.