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Journal of Dispersion Science and Technology Volume 30, 2009 - Issue 2
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Original Articles

Self-Assembly of Tryptophan-Capped Gold Nanoparticles onto DNA Network Template

Zahra Sheikholeslami Department of Chemical and Petroleum Engineering, Sharif University of Technology, Tehran, Iran
,
Manouchehr Vosoughi Department of Chemical and Petroleum Engineering, Sharif University of Technology, Tehran, Iran; Institute of Nano-Science and Nano-technology, Sharif University of Technology, Tehran, IranCorrespondence[email protected]
&
Iran Alemsadeh Department of Chemical and Petroleum Engineering, Sharif University of Technology, Tehran, Iran
Pages 255-259 | Received 19 Nov 2007, Accepted 19 Nov 2007, Published online: 28 Jan 2009
 
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Abstract

In this study, a simple route to the formation of DNA-gold complex has been reported, using immobilized DNA as a template. The nanoporous gold films have been prepared by the electrostatic self assembly of gold nanoparticles capped with tryptophan. Tryptophan would improve surface properties of gold nanoparticles for strongly attaching to DNA. Fourier transform infrared spectroscopy confirmed that gold nanoparticles have been capped by tryptophan. Also measured zeta potential shows that there are positive charges on the surface of gold nanoparticles. Investigations by atomic force microscopy substantially confirm that tryptophan-capped gold nanoparticles can be bonded to DNA template electrostatically.

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