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Journal of Dispersion Science and Technology Volume 30, 2009 - Issue 4
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Original Articles

Characterization and Antimicrobial Evaluation of Dilution-Stable Microemulsions Against Stenotrophomonas maltrophilia

Fengqin Feng Department of Food Science and Nutrition, Huajiachi Campus, Zhejiang University, Hangzhou, China
,
Hui Zhang Department of Food Science and Nutrition, Huajiachi Campus, Zhejiang University, Hangzhou, China
,
Sha Sha Department of Food Science and Nutrition, Huajiachi Campus, Zhejiang University, Hangzhou, China
,
Zhonghua Lu Department of Food Science and Nutrition, Huajiachi Campus, Zhejiang University, Hangzhou, China
,
Yan Shen Department of Food Science and Nutrition, Huajiachi Campus, Zhejiang University, Hangzhou, China
&
Xiaodong Zheng Department of Food Science and Nutrition, Huajiachi Campus, Zhejiang University, Hangzhou, ChinaCorrespondence[email protected]
Pages 503-509 | Received 23 Dec 2007, Accepted 10 Jan 2008, Published online: 26 Mar 2009
 
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Abstract

The purpose of this study is to load glycerol monolaurate (GML) in a microemulsion system for the inactivation of Stenotrophomonas maltophilia. The influence of ethanol, propylene glycol (PG) and sodium benzoate (Na-Bz) on oil solubilization of GML microemulsions is clearly reflected in the phase behavior of these systems. One dilution-stable microemulsion formulation was determined and stable by the examination of the physical stability. Results showed that the microemulsion at 100 ppm, comparable to 3 mg/L ceftazidime, had much higher antimicrobial activities against S. maltophilia, with a major contribution of GML, and Na-Bz enhanced the antimicrobial activities as a hydrotrope.

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