Fusion Dynamics of Aqueous Glutamic Acid/Aminodecane/Ibuprofen Vesicles

Abstract

Vesicles have been prepared at a constant molar ratio of L-glutamic acid/1-aminodecane/ibuprofen/H₂O. The fusion dynamics of the vesicles have been directly observed and followed by using optical microscopy and freeze fracture replication-electron microscopy technologies. With time increasing up to 25 minutes, the vesicles slowly fuse to form large stable vesicles. A membrane phase transition temperature is detected at 97°C.

Keywords:

• Behavior
• dynamics
• fusion
• interface
• vesicle

This work was supported by the National Natural Science Foundation of China (20573091) and the Foundation of the Educational Committee of Jiangsu Provincial Universities Excellence Science and Technology Invention Team in Yangzhou University.