Recent Developments in the Synthesis and Chemistry of 2(1H)-Pyridinethiones and Related Compounds

Abstract

The synthesis of 2(1H)-pyridinethiones from acyclic and cyclic starting materials is reviewed. The chemistry of the 2(1H)-pyridinethiones and the use of such compounds in organic synthesis is also covered with special emphasis on the annellation reactions for the preparation of fused heterocyclic systems. The coverage of other sulfur-containing pyridines is less extensive.

Key Words:

• 2(1H)-Pyridinethiones
• 4(H)-pyridinethiones
• alkylation
• acylation
• desulfuration
• S-dealkylation
• nucleophilic substitution
• annellation reactions
• redox reactions