Effect of asthma and six-months high-intensity interval training on heart rate variability during exercise in adolescents

ABSTRACT

Little is known regarding the influence of asthma and exercise, and their interaction, on heart rate variability (HRV) in adolescents.

Thirty-one adolescents with asthma (13.7±0.9 years; 21.9±3.9 kg·m⁻²; 19 boys, 12 girls) and thirty-three healthy adolescents (13.8±0.9 years; 20.3±3.2 kg·m⁻²; 16 boys, 17 girls) completed an incremental ramp test and three heavy-intensity constant-work-rate cycle tests. Thirteen adolescents (7 boys, 6 girls; 6 asthma, 7 control) completed six-months high-intensity interval training (HIIT) and were compared to age- and sex-matched controls. Standard time-domain, frequency-domain and non-linear indices of HRV were derived at baseline, three- and six-months.

Asthma did not influence HRV at baseline or following HIIT. Total power, low frequency and normalised low frequency power, and sympathovagal balance increased at three-months in HIIT, subsequently declining towards baseline at six-months. Normalised high frequency power was reduced at three-months in both groups, which was sustained at six-months. No effects of HIIT were observed in the time-domain nor in the non-linear indices.

HRV was not influenced by asthma, potentially because such derangements are a function of disease progression, severity or duration. HIIT may be associated with a short-term shift towards greater sympathetic predominance during exercise, perhaps caused by physiological overload and fatigue.

KEYWORDS:

• Heart rate variability (HRV)
• youth
• exercise
• non-linear
• children

Disclosure statement

No potential conflict of interest was reported by the authors.

Additional information

Funding

This work was funded by the Asthma UK Centre for Applied Research [AUK-AC-2012-01] and Swansea University Medical School. Commando Joe’s® supported the work and assisted in funding co-author WTBE.