Abstract
Human tolerance limits for sustained operations under the combined stress of stale air and sleep loss were studied in two groups often male volunteers over a 72 h period, with only 1h of sleep permitted after 32, 48 and 60h. The experiment investigated whether such sustained performance might be additionally influenced by mild hypoxia (15 vol% O2) together with correspondingly increased carbon dioxide levels (5 vol%).
Performance on various psychological tests showed the expected decrease with increasing duration of sleep loss. However, there were no clear cut differences in performance between the control and the hypoxia groups. There were, however, more pronounced decreases with time in either group in the more complex tasks as compared to simple reaction time and vigilance tasks. Short-term memory improved probably due to learning. The missing effect of hypoxia could be attributed to a hyperventilation response in the experimental subjects and an increase in cerebral blood flow initiated by the hypercapnia.