Positive mood and sleep disturbance in acquired mania following temporal lobe damage

Abstract

Primary objective: To determine the mood profile and sleep functioning of a patient with left anterior temporal region damage characterized by post-operative symptoms of mania.

Methods and procedures: In a structured clinical assessment, the patient's mood status, psychiatric diagnosis and sleep functioning—sleep onset latency, total sleep time, wake after sleep onset—were assessed. The sleep–wake cycle and daily mood was measured for 11 consecutive days.

Results: The patient met diagnostic criteria for bipolar disorder (excluding the requirement that the disturbance must not be due to a medical disorder) and delayed sleep-phase syndrome. Across 11 days, the patient exhibited elevated positive, but not negative, mood. Correlational analyses indicated a possible association between mood and sleep disturbance.

Conclusions:This pattern of findings implicates the temporal lobe in positive mood regulation and sleep-related impairments.

• Mania
• positive mood
• sleep
• temporal lobe
• delayed phase