Effect of UV-absorbing Contact Lenses on Conjunctival Ultraviolet Autofluorescence

ABSTRACT

Purpose

The intended purpose of UV-absorbing contact lenses is to protect the cornea and posterior ocular structures from UV-induced damage. Few studies report conjunctival effects of UV-absorbing contact lens materials. The purpose of this study was to evaluate conjunctival ultraviolet autofluorescence (UVAF) for contact lens wearers of UV-absorbing and minimally UV-absorbing materials.

Methods

Forty-four volunteers enrolled in the cross-sectional study. Three groups were recruited; non-contact lens wearers (n = 15), minimally UV-absorbing contact lens wearers (n = 15), and UV-absorbing contact lens wearers (n = 14). Ocular sun exposure was calculated using self-reported measures. Conjunctival UVAF images of temporal and nasal conjunctiva, acquired using a Nikon D7000 camera system adapted with appropriate flash and filter system, were analyzed using ImageJ. A sub-group of participants including only subjects with measurable UVAF was analyzed.

Results

No significant differences were present between groups found similar for age, gender, and ocular sun exposure. The area of UVAF significantly increased following lens removal for UV-absorbing contact lens wearers compared with non-contact lens wearers. Furthermore, for contact lens wearers compared with non-lens wearers, area of UVAF was significantly greater between right and left eyes (p = .04 minimally UV-absorbing, p = .01 UV-absorbing), and between nasal (p = .046 minimally UV-absorbing, p = .01 UV-absorbing), and temporal (p = .01 UV-absorbing) areas. However, no significant difference was found between contact lens wearers of the two groups. No difference was found between nasal and temporal UVAF regions during contact lens wear (p = .28) or after lens removal (p = .16) (Mann–Whitney U).

Conclusions

Contact lens materials have conjunctival effects, with increased UVAF in both UV-absorbing and minimally UV-absorbing contact lens wearers compared with non-lens wearers. UV-absorbing and minimally UV-absorbing contact lens materials appear to influence nasal and temporal areas of the ocular surface equally.

KEYWORDS:

• Conjunctival
• autofluorescence
• contact lenses
• ultraviolet
• ocular sun exposure

Conflict of interest

The authors have no conflicts of interest to declare.

Additional information

Funding

This work was supported by the Southern College of Optometry [Internal institutional funding].