Comparing the Early Changes in Classified Higher-Order Aberrations Before and After Non-Toric and Toric Implantable Collamer Lens V4c Implantation

Abstract

Purpose

This study aimed to compare early changes in classified higher-order aberrations (HOAs) pre- and postsurgery in patients who received nontoric versus toric implantable collamer lenses (ICL; ICL Model V4c; STAAR Surgical, Monrovia, CA, USA).

Methods

This prospective study included 124 eyes of 64 patients: 49 eyes were treated using a nontoric implantable collamer lens (ICL), and 75 eyes were treated using a toric implantable collamer lenses (TICL). Refractive parameters and ocular aberrations were examined before and 1 month after surgery.

Results

At one month, the safety indices were 1.24 ± 0.17 in the ICL group and 1.20 ± 0.25 in the TICL group (p = 0.39). The efficacy indices were 1.07 ± 0.17 in the ICL group and 1.15 ± 0.26 in the TICL group (p = 0.02). The root mean square (RMS) values of whole-eye total HOAs, trefoil, corneal total HOAs, spherical aberration, and intraocular spherical aberration significantly increased postoperatively in both groups. The RMS of intraocular total HOAs in the TICL group significantly increased 1 month postoperatively. No statistically significant differences were observed in HOA changes between the ICL and TICL groups.

Conclusions

The dominant increases in short-term aberrations after ICL and TICL V4c implantation were in corneal trefoil and intraocular spherical aberrations, which were related to the corneal incision and implanted lens. The HOA changes post-surgery were not statistically different between the two lens types.

Keywords:

• ICL
• TICL
• higher-order aberrations
• myopia
• astigmatism

Authors’ contributions

The authors were involved in the conception or design of the work, the acquisition, analysis or interpretation of data for the work (ICL, XC, MRC, HMM, BLL, YJJ, YDL, YLX, XYW, XTZ); drafting the work or revising it critically for important intellectual content (ICL, XC); final approval of the version to be published (XYW, XTZ); agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved (ICL, XC, MRC, HMM, BLL, YJJ, YDL, YLX, XYW, XTZ). All authors read and approved the final manuscript

Ethics approval and consent to participate

This study was conducted in accordance with the principles of the Declaration of Helsinki and was approved by the Ethics Committee of the Eye and ENT Hospital Review Board of Fudan University (2021018). Written informed consent was obtained from all patients after the nature and possible consequences of the study were explained.

Consent for publication

Written informed consent was obtained from the patient for publication of this paper.

Disclosure statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Data availability statement

Data and materials are available upon request from the corresponding author at [email protected] or [email protected].

Additional information

Funding

This study was supported by National Natural Science Foundation of China (Grant No. 81770955 and 82171095), Project of Shanghai Science and Technology (Grant No. 20410710100 and 19140900700), Clinical Research Plan of SHDC (Grant No. SHDC2020CR1043B), Project of Shanghai Xuhui District Science and Technology (Grant No. 2020-015, XHLHGG202104), Shanghai Engineering Research Center of Laser and Autostereoscopic 3D for Vision Care (Grant No. 20DZ2255000), Construction of a 3D digital intelligent prevention and control platform for the whole life cycle of highly myopic patients in the Yangtze River Delta (Grant No. 21002411600).