Impact of moderate-severe persistent allergic rhinitis on thoraco-abdominal kinematics and respiratory muscle function

Abstract

Objective: To assess thoraco-abdominal kinematics, respiratory muscle strength and electromyographic activity of the diaphragm (EAdi) in moderate-severe allergic rhinitis (AR) patients. Methods: A cross-sectional study involving 40 individuals (20 in the AR group) and 20 in the control group [CG]) was conducted. Ventilatory pattern and chest wall volume distribution (optoelectronic plethysmography), respiratory muscle strength (manovacuometry and sniff nasal inspiratory pressure [SNIP]), and EAdi were assessed in both groups. Results: The AR patients had impaired thoraco-abdominal kinematics (reduced total chest wall volume) (p = 0.004), lower values of total respiratory cycle time (p = 0.014) and expiratory time (p = 0.006). They also presented an increase of percentage contribution of the abdominal rib cage (p = 0.475) and respiratory rate (p = 0.019). A positive correlation among pulmonary rib cage tidal volume and MIP (r = 0.544; p < 0.001), SNIP (r = 0.615; p < 0.001), and MEP (r = 0.604; p < 0.001) was observed. After adjusting for age, BMI and gender through multivariate analysis, the individuals with AR presented lower values ​​of MIP (β = −24.341; p < 0.001), MEP (β = −0.277; p < 0.001), SNIP (β = −34.687; p < 0.001) and RMS (β = −0.041; p = 0.017). Conclusions: The individuals with moderate-severe persistent AR had worse respiratory muscle strength, diaphragm activation and chest wall volume distribution with a higher abdominal contribution to tidal volume than the control group. These findings reinforce the notion that the upper and lower airways work in an integrated and synergistic manner.

Keywords:

• Allergic rhinitis
• respiratory muscles
• lung function
• maximal inspiratory pressure
• muscle weakness
• diagnostic techniques

Acknowledgements

Founding by Fundação de Amparo a Ciência e Tecnologia do Estado de Pernambuco (FACEPE) APQ-0154-4.08/15 and Coordenação de Aperfeiçoamento de Pessoal de Nıv´el Superior (CAPES)/Programa Nacional de Cooperação Acadêmica (PROCAD). 88881.068409/2014-0.

Declaration of interest

The authors report that they have no conflicts of interest. The authors alone are responsible for the content and writing of the paper.