The relationship between general and abdominal obesity, nutrition and respiratory functions in adult asthmatics

Abstract

Objective

Although obesity is known to have adverse effects on asthma, it is not fully known whether general or abdominal obesity affects asthma symptoms more. In this study, the effects of diet and general/abdominal obesity on respiratory functions were evaluated.

Methods

A total of 204 adult asthmatic individuals participated in the study. Anthropometric measurements, respiratory functions, asthma control test (ACT) scores, and 24-hour food consumption were recorded. The results were compared according to body mass index (BMI), waist circumference (WC), and waist-hip ratio (WHR) classification.

Results

FEV₁, FVC, MEF_25-75, MEF₅₀, and MEF₂₅ decreased with the increase in BMI, WC, and WHR. FEV₁ showed a negative linear relationship with BMI, WC and WHR and these results were more significant in WC and WHR than BMI. Similarly, the ACT score also showed a negative correlation with BMI (r = −0.372; p = 0.023), WC (r = −0.402; p = 0.001) and WHR (r = −0.387; p = 0.011), and the results were more significant in WC and WHR than BMI. Individuals whose WC (OR: 2.170 CI (1.325-3.182)) and WHR (OR: 2.119 CI (1.246-3.338)) were at risk had higher odds of uncontrolled asthma than those with normal WC and WHR. Each 100-kcal increase in total energy consumption increased the odds of uncontrolled asthma (OR: 1.125 CI (1.086-2.217)) (p < 0.05).

Conclusions

The effects of WC and WHR, which are indicators of abdominal obesity, on respiratory functions and ACT score, were found to be higher than BMI. Obese individuals should be referred to diet clinics to improve their asthma symptoms.

Keywords:

• Asthma
• general obesity
• central obesity
• nutrition

Acknowledgements

The authors would like to thank J. Ahmed Nizamani for his support and knowledge.

Disclosure statement

No potential conflict of interest was reported by the authors.

Funding

The author(s) reported there is no funding associated with the work featured in this article.