In vitro fungitoxic activity of some Schiff bases and their oxovanadium(IV) complexes

Abstract

The oxovanadium(IV) (VO(IV)) complexes, Schiff bases, vanadyl sulphate, standard fungicides (bavistin and emcarb) and control (dimethyl sulphoxide) were tested for their in vitro fungitoxic activity on A. niger, F. oxysporum and A. flavus. The oxovanadium(IV) complexes show higher fungitoxic activity as compared with the free ligands, vanadyl sulphate and control (dimethyl sulphoxide), but moderate fungitoxic activity as compared with the standard fungicides (bavistin and emcarb). Oxovanadium(IV) complexes have been prepared with biologically active Schiff bases viz. the potassium salt of salicylidene-DL-alanine (sal-ala), 2,2′-bipyridylamine (bipym), bis(benzylidene)ethylenediamine (benen), thiophene-o-carboxaldeneaniline (tca), thiophene-o-carboxaldene-p-toluidine (tct), bis(benzylidene)-1,8-diaminonaphthalene (bendan) or bis(acetophenone)ethylenediamine (acphen). They have been characterized on the basis of elemental analysis, thermogravimetric analysis, magnetic measurements, electronic and infrared spectra. An octahedral geometry has been tentatively assigned to all the complexes.

Keywords:

• Oxovanadium(IV) complexes
• Schiff bases
• fungitoxic activity
• fungicides
• octahedral geometry

Acknowledgement

The authors express their gratitude to the Head of the Department of Chemistry, and to the Head of the Department of Bio-sciences, Sardar Patel University, Vallabh Vidyanagar, India, for providing the necessary laboratory facilities.