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Toxicological & Environmental Chemistry Volume 91, 2009 - Issue 3
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Original Articles

Protective influence of antioxidant vitamins on hematological indices of rabbits fed crude-oil-contaminated diet

F.I. Achuba Department of Biochemistry, Delta State University, PMB 1 Abraka, NigeriaCorrespondence[email protected]
&
P.E. Awhin Department of Medical Biochemistry, Delta State University, Abraka, Nigeria
Pages 505-510 | Received 11 Aug 2008, Accepted 10 Oct 2008, Published online: 05 May 2009
 
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Abstract

The effects of chronic exposure to petroleum on hematological parameters as well as the possible protective role of vitamins E and C were studied. The hematological parameters assessed were red blood cell (RBC) counts, hematocrit, hemoglobin concentration, and white blood cell (WBC) counts. The RBC and hemoglobin concentration were significantly decreased in the blood of petroleum-fed rabbits. However, there was a significant increase in WBC in rabbits exposed to crude-oil-contaminated feed. Pretreatment with the antioxidant vitamins E and C restored these parameters to normal.

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