Fluoride content of Ethiopian khat (Catha edulis Forsk) chewing leaves

Abstract

The levels of water soluble and total fluoride concentration in 11 different varieties of Ethiopian khat (Catha edulis Forsk, an evergreen stimulant plant) commonly consumed in the country and exported to the neighboring countries were determined by fluoride ion-selective electrode. Known amounts of fresh khat samples were suspended in deionized water, stirred, and the supernatants exposed to a chelator that decomplexes fluoride were assayed. The total fluoride concentration in the leaves was also analyzed after the leaves were dried, charred, and ashed. Water soluble and total fluoride concentration in khat varieties varied, ranging from 0.19 to 0.43 µg g⁻¹ fresh weight and 3.4 to 7.1 µg g⁻¹ dry weight, respectively. The fluoride concentration in matured leaves (12 µg g⁻¹) was higher than that in young leaves (6.5 µg g⁻¹) dry weight. Assuming that daily khat leaves chewing for an adult is 100 g, fluoride intake from chewing leaves of the analyzed khat varieties is far below the daily fluoride tolerable upper limit. The safe intake of fluoride is recommended to be 1.5–4.0 mg day⁻¹ for adults and less for children. However, chewing khat leaves may contribute a significant amount of fluoride for the total daily intake of an individual and should not be overlooked while estimating the total dietary intake of fluoride for individuals chewing khat leaves regularly.

Keywords:

• khat
• Catha edulis Forsk
• fluoride
• Ethiopia

Acknowledgments

The authors express their gratitude to the Department of Chemistry, Addis Ababa University, Ethiopia, for providing the laboratory facilities. Minaleshewa Atlabachew is thankful to the Department of Chemistry, Bahir Dar University, Ethiopia, for sponsoring his study.