Validation of QuEChERS-based method for determination of flusilazole residues in grape by high-performance liquid chromatography with photodiode array detector

Abstract

A high-performance liquid chromatography with photodiode array detector analytical method was developed to determine the residue levels of flusilazole in grape and investigate the dissipation pattern and safety. The results showed that the mean recoveries were in the range of 86%–90%. Limits of detection and quantification were 0.008 and 0.02 mg/kg, respectively. The residue levels of flusilazole were best described by first-order rate kinetics and with half-lives ranging from 4.2 days (recommended dose) to 4.6 days (double the recommended dose). In conclusion, flusilazole at the recommended or even at double the recommended doses does not pose any apparent hazards to consumers.

Keywords:

• dissipation
• risk assessment
• flusilazole
• residues
• HPLC-DAD

The authors thank all members and staff of Pesticide Residues and Environmental Pollution Department, Central Agricultural Pesticides Laboratory, Agriculture Research Centre, Egypt, for their technical assistance. The authors are grateful to Professor Abd El-Aty Mostafa Abd El-Aty for his contribution to improve this article.

Disclosure statement

No potential conflict of interest was reported by the authors.