The Domino Effect: Ed Domino’s early studies of Psychoactive Drugs

ABSTRACT

University of Michigan Pharmacology Professor Ed Domino is an expert in the field of neuropsychopharmacology. For over six decades, Dr. Domino has made many contributions to our understanding of psychoactive drugs, but is most well-known for his role in the development of ketamine anesthesia. This article covers the story behind this discovery, along with many other fascinating personal and professional anecdotes, all of which provide insight into the career of a remarkable scientist.

KEYWORDS:

• Ed Domino
• history
• ketamine
• psychopharmacology

Acknowledgments

The author would like to thank Mason Amin, Kathleen Baines, Justin Clark, Jaclyn Denomme, Ken Domino, Jacob Hull, Dr. Lori Isom, Dr. George Mashour, Hamilton Morris, Kaylee Sistek, the University of Michigan Department of Pharmacology, and, of course, Dr. Ed Domino.