Abstract
Purpose: to evaluate the morphologic substrate of the rim enhancement of colorec-tal metastases seen at CT during infusion hepatic arteriography (CTIHA)
Material and Methods: Eleven sector defects in the enhancing rim of 9 metastases at CTIHA were analyzed. the corresponding pathologic specimens were investigated for sector defects of liver parenchyma. We investigated whether there was a correlation between the central angle of the sector defects of rim enhancement at CTIHA and that of sector defects in the zone of liver parenchyma in histologic slices. the inner and outer diameters of the enhancing rim were also compared with the diameter of the metastases as seen at CT during arterial portography (CTAP)
Results: There was a significant correlation between the central angle of sector defects of rim enhancement at CTIHA and the angle of sector defects in the zone of liver parenchyma in histologic slices (p=0.008, Spearman's test). the diameter of the metastases measured at CTAP was larger than the inner diameter and smaller than the outer diameter of the enhancing rim in CTIHA, i.e. the margins of the nodules as seen in CTAP are located in liver parenchyma and not in tumor tissue
Conclusion: the morphologic substrate of the rim enhancement of colorectal metastases seen at CTIHA is liver parenchyma
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