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Short communication

Lack of serological homology between chicken alpha‐foetoprotein, chicken foetal red blood cell antigen and Marek's disease tumour‐associated surface antigenFootnote1

Pages 597-601 | Received 26 Feb 1980, Published online: 12 Nov 2007
 

Summary

In the course of immunofluorescence absorption studies it was found that, besides Marek's disease tumour‐associated surface antigen (MATSA), two foetal antigens could be distinguished on MSB‐1 line cells, one of which was chicken foetal red blood cell antigen (chFRBC) and another chicken alpha‐foetoprotein (chAFP). The experiments suggest a lack of homology between the three antigens.

Resume

Au course des études d'absorption en immunofluorescence, il a été trouvé qu'en plus de l'antigène de surface associé aux tumeurs de la maladie de Marek, (MATSA) deux antigènes foetaux pouvaient être mis en évidence sur cellules de lignée MSB‐1, l'un d'entre eux était l'antigène de globules rouges foetaux de poulet (Ch FRBC) et l'autre l'alpha‐foeto protéine de poulet (Ch AFP). Les résultats d'expérience suggèrent une absence d'homologie entre les trois antigènes.

Zusammenfassung

Immunfluoreszenz‐Absorptions‐Untersuchungen lassen darauf schlieβen, daβ neben dem “Marek's disease tumor‐associated surface antigen” (MATSA) mindestens zwei fetale Antigene auf der Oberfläche von MSB‐1‐Zellen exprimiert werden. Dabei handelt es sich um ein fetales Hühnererythrozyten‐Membranantigen (chFRBC) sowie um Hühner‐alpha‐Fetoprotein (chAFP). Alle drei Antigene erwiesen sich serologisch als untereinander nicht verwandt.

Notes

Partly supported by the Deutsche Forschungsgemeinschaft

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