Abstract
1-Aminoalkylphosphonic acids 1 as analogs of 1-amino-carboxylic acids are important because of their potential biological activity. These act as substrates or inhibitors of enzymes involved in the metabolism of amino acids. Several phosphono dipeptides and oligopeptides are known to repress bacterial growth. Many of these studies have been carried out using racemic l-amino- alkylphosphonic acids 1 although in several cases their activity has been shown