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Original Articles

CAMPHOR-AND 10-SULFONAMIDOCAMPHOR SULFONOHYDRAZONES AND RELATED COMPOUNDS

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Pages 91-97 | Received 26 Feb 1988, Accepted 17 May 1988, Published online: 13 Dec 2006
 

Abstract

Camphor-10-sulfonyl chloride (1) was converted into the hydrazide (3), the N-phenyl- and N,N 1-dimethylhydrazides (14,15); the former was characterized as the hydrazones (5–9) and the 3,5-dimethylpyrazole (10). Camphor-10-sulfonanilide (17) and the morpholidate (19) were condensed with hydrazine hydrate, to give the hydroazones (18,20) converted into the azines (21–30). Camphorhydrazone was similarly prepared, together with the azines (31–37). The spectral data are briefly discussed together with the results of preliminary biological screening.

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