New synthetic mitral valve model for human prolapsed mitral valve reconstructive surgery for training

Abstract

The training process of young surgeons is highly desirable in order for them to gain an understanding of the quality of care and patient safety required during cardiac surgeries, however, it may take a few years of practice in order for them to properly develop these skills. Artificial life-like platforms and models are extremely recommended for teaching hands-on and real-world practice in both junior and even experienced medical professionals and surgeons. Suitable and accessible training tools are of significant importance for simulating a particular surgery in order to provide practice opportunities for a specific surgical procedure. In this study, we focussed on the simulation of the human mitral valve prolapse reconstructive surgery. An innovative, artificial, biomimetic model was designed and fabricated made of Cryogel biomaterial developed in our lab that is suitable for the precise practice on the mitral valve prolapse model. The proposed model is mainly made up of polyvinyl alcohol (PVA) cryogel, which is designed to resemble the geometric and mechanical properties of a diseased (prolapse) mitral valve. We simulated the constructive prolapsed mitral valve surgery entirely on a synthetic platform. The platform was made available to four certified cardiac surgeon and there were unanimously very positive with no considerable differences in the procedural assessments between them. The proposed model has a similar appearance and texture to that of a diseased mitral valve and holds consistent mechanical properties to those of the real tissue. The offered technology may be used for other cardiothoracic reconstructive surgeries with high precision and consistency.

Keywords:

• Heart valve mechanics
• mitral valve prolapse
• PVA cryogel
• surgical simulation
• synthetic models

Compliance with ethical standards

All prerequisites requested in the Instructions to Authors are fulfilled.

Statement of human and animal studies

This study is completely based on synthetic materials and does not involve in any animal or human studies.

Disclosure statement

No potential conflict of interest was reported by the author(s).

Additional information

Funding

NSERC/Discovery Grant and University of British Columbia.