Parameters of high-frequency jet ventilation using a mechanical lung model

Abstract

High frequency jet ventilationis a mechanical lung ventilation method which uses a relatively high flow usually through an open system. This work examined the effect of high-frequency jet ventilation on respiratory parameters of an intubated patient simulated using a high-frequency jet ventilator attached to a ventilation monitor for measurements of ventilation parameters. The series of experiments altered specific parameters each time (respiratory rate, inspiratory-expiratory (I:E) ratio, and inspiratory pressure), under different lung compliances. A reduction of minute ventilation was observed alongside a rise in respiratory rate, with low airway pressures over the entire range of lung compliances. In addition, an I:E ratio of 2:1 to 1:1; and the tidal and minute volumes were directly related to the inspiratory pressure over all compliance settings. To conclude, the respiratory mechanics in high-frequency jet ventilation are very different from those of conventional rate ventilation in a lung model. Further studies on patients and/or a biological model are needed to investigate pCO2 and end-tidal carbon-dioxide during high-frequency jet ventilation.

Keywords:

• High-frequency jet ventilation
• tidal volume
• minute volume
• respiratory rate
• inspiratory to expiratory ratio
• lung compliance
• lung model

Acknowledgments

The authors are grateful to Mrs. Tobie Kuritsky and to Galilee-CBR for the editorial proof.

Disclosure statement

No potential conflict of interest was reported by the authors.