Simultaneous detection of four pesticides in agricultural products by a modified QuEChERS method and LC-MS/MS

Abstract

A modified QuEChERS pretreatment method and LC-MS/MS technique were performed to simultaneously determine four pesticide (Hexachlorophene, Dinex, Dinosam, Dinoterb) residues in agricultural products. Through the optimization of LC-MS/MS detection parameters in SIM mode, the optimal instrument conditions are obtained. The modified QuEChERS method was used to pretreat the samples. Solid phase extractants PSA, C18 and GCB were used for sample purification. The research results showed that the correlation coefficients of the four pesticides were all greater than 0.991, which had a good linear relationship. The limits of quantitation (LOQ) of the four pesticides were 0.05–0.56 μg/kg. The recoveries were 70.51–113.20% with relative standard deviations (RSDS) of 1.6–11.2%. The developed method can provide reliable data support for the subsequent simultaneous detection of these four pesticides.

Keyword:

• Pesticides
• agricultural products
• QuEChERS
• LC-MS/MS
• detection

Disclosure statement

The authors declare that they have no conflicts of interest.

Data availability statement

Data supporting the findings of this study are available from the respective authors upon reasonable request.

Additional information

Funding

This study was supported by the Science and Technology Research Project of the Education Department of Jiangxi Province [GJJ2202411], Subject Construction Project of Jingdezhen Science and Technology Plan [20202GYZD015-07], and the Innovation and Entrepreneurship Training Program for College Students of Jingdezhen University [202210894011].