Advanced search
Publication Cover
Journal of Environmental Science and Health, Part B
Pesticides, Food Contaminants, and Agricultural Wastes
Volume 20, 1985 - Issue 2
Submit an article Journal homepage
31
Views
19
CrossRef citations to date
0
Altmetric
Original Articles

Mutagenicity tests with gallic and tannic acid in the salmonella/mammalian microsome assay

Kamal A. Rashid Pesticide Research Laboratory and Graduate Study Center Department of Entomology, The Pennsylvania State University, USA
,
Ian I. Baldwin Pesticide Research Laboratory and Graduate Study Center Department of Entomology, The Pennsylvania State University, USA
,
John G. Babish Department of Preventive Medicine New York State College of Veterinary Medicine, Cornell University, Ithaca, NY, 14853, USA
,
Jack C. Schultz Pesticide Research Laboratory and Graduate Study Center Department of Entomology, The Pennsylvania State University, USA
&
Ralph O. Mumma Pesticide Research Laboratory and Graduate Study Center Department of Entomology, The Pennsylvania State University, USA
Pages 153-165 | Received 27 Nov 1984, Published online: 21 Nov 2008
 
Sample our Engineering & Technology journals, sign in here to start your access, latest two full volumes FREE to you for 14 days

Abstract

Gallic acid, tannic acid mixture and a purified fraction of tannic acid were evaluated for possible mutagenlc activity in three strains of Salmonella typhimurium, TA98, TA100, and TA1535. These chemicals were not mutagenic either before or after activation with rat and woodchuck microsomal and cytosolic enzymes. However, tannic acid mixture and tannic acid fraction both gave a significantly (p = 0.05) dose‐related reduction in the number of the revertant colonies, compared to the normal spontaneous rever‐tants with no apparent toxic effects in the background lawn. With an agar diffusion assay, the chemicals exhibited toxic effects at 5000 μg/disc.

Notes

Visiting Professor from the University of Salah Addeen, Arbil,

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related Research Data

Detection of carcinogens as mutagens: bacterial tester strains with R factor plasmids.
Source: Proceedings of the National Academy of Sciences
Lower limits of molecular weights of compounds excluded from sephadex G-25 eluted with aqueous acetone mixtures : Application of the results to the separation of the components of tannic acid
Source: Elsevier BV
Naturally Occurring Food Toxicants: Phenolic Substances of Plant Origin Common in Foods
Source: Elsevier
Determination of drug metabolizing enzymes in needle biopsies of human liver.
Source: Springer Science and Business Media LLC
Evaluation of chlordimeform and degradation products for mutagenic and DNA-damaging activity in Salmonella typhimurium and Escherichia coli
Source: Informa UK Limited
A gas-liquid chromatographic method for analysis of phenolic acids in plants
Source: American Chemical Society (ACS)
Toxicological Aspects of Antioxidants Used as Food Additives
Source: Springer Netherlands
The condensed tannins of pasture legume species
Source: Elsevier BV
Induction of tumours by tannin extracts.
Source: Springer Science and Business Media LLC
Toxicity and related physiological activity of phenolic substances of plant origin
Source: American Chemical Society (ACS)
Vegetables inhibit, in vivo, the mutagenicity of nitrite combined with nitrosable compounds
Source: Elsevier BV
The inhibition of enzymes by tannins
Source: Elsevier BV
The Saldanha skull and its associations.
Source: Springer Science and Business Media LLC
REVISED METHODS FOR THE SALMONELLA MUTAGENICITY TEST
Source: Elsevier BV
Recommendations on data production and analysis using the salmonella/microsome mutagenicity assay
Source: Wiley

Linking provided by 

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.