Abstract
Novel amphiphilic block copolymers poly(citric acid)-b-poly(L-lactide)-b-poly(citric acid), (PCA-PLA-PCA), were synthesized by melt polycondensation reaction of citric acid and hydroxyl telechelic poly(L-lactide). The chemical structure of the resulting copolymers was characterized by various analytical techniques. DSC data showed the higher glass transition and melting temperature for copolymer suggesting increased crystallinity confirmed by X-ray diffraction data. The effects of the segment length of both the PLA and the PCA portions on the sizes of the PCA-PLA-PCA polymeric micelles were investigated. The results indicated that the size of the polymeric micelle reflects the chain length of both types of segments in the copolymer.
ACKNOWLEDGMENTS
The authors are grateful to Industrial Connection Office of University of Tabriz for financial supports and Dr. Mohsen Adeli for his efficient collaborations.
Notes
a1HNMR in CDCl3.
b Number of lactide units.
a Co-initiator/L-lactide molar ratio.
b PLA/citric acid molar ratio.
c1H NMR in d 6-DMSO.