Development and Characterization of Soy Lecithin and Palm Oil-based Organogels

Abstract

Preparation and characterization of soy lecithin (SL) and palm oil (PO) based organogels have been reported in this study. The optimization of the composition of the organogels was carried out by varying the proportions of SL, PO and water. Microscopic studies suggested the presence of aqueous phase either as spherical droplets or fluid filled fibers or both, depending on the composition of the organogels. FTIR study indicated strong intermolecular hydrogen bonding among the organogel components. The release of metronidazole (model drug, MZ) suggested diffusion mediated drug release. MZ loaded organogels showed good antimicrobial property against B. subtilis and E. coli.

Keywords:

• Antimicrobial
• Diffusion
• Hemocompatible
• Organogels
• Palm oil
• Soy lecithin

Notes

Authors Baran and Singh contributed equally to this work.

Color versions of one or more of the figures in the article can be found online at www.tandfonline.com/lpte.