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Original Articles

Nanostarch Reinforced with Chitosan/Poly (vinyl pyrrolidone) Blend for In Vitro Wound Healing Application

, &
Pages 1400-1410 | Published online: 20 Oct 2017
 

ABSTRACT

Nanostarch, which is inexpensive and environmentally abundant, has been used as filler to prepare biocompatible films. The bio-nanocomposites were synthesized by solution casting method. TEM analysis proves that the average particle size of the nanostarch is in the range of 20–40 nm. Thermal stability and cell viability of CS/PVP matrix were best enhanced at 1% of nanostarch loading. The antibacterial activity exhibited by CPS bio-nanocomposite against Staphylococcus aureus and Pseudomonas aeruginosa and synergistic effects of CPS such as barrier properties, swelling properties, and better blood compatibility make it a suitable material for in vitro wound healing application.

GRAPHICAL ABSTRACT

Acknowledgement

The authors are grateful to Auxilium College Management for providing necessary facilities for the experimental work.

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