![Sample our Behavioral Sciences journals, sign in here to start your access, latest two full volumes FREE to you for 14 days]({"type":"image" , "src" : "/sda/110801/TOC-Subject-Sample-2021-Behavioral-Sciences.jpg"})
Abstract
The effect of aging on Ca2+ -transport in synaptosomal preparations from rat brains was assessed by measuring the accuinulation of radioactive 45Ca within these particles. Four groups of rats at 6, 12 24 and 30 months of age were used for this study. Synaptosomal particles were isolated from the cerebral cortes of each animal and the radioactive 45Ca inside the particles were ineasured after incubating the particles with media containing an energy source and 45Ca C12. Results indicated that the transport of 45Ca was lower in the younger rats than the older groups. A 20% increase uw consistent with the old rats (30 mo) as compared with the young ones (6 mo). The increase in Ca2+ -transport across synaptic plasma membranes may be related to the transmitter release and behavioral activity after senescence.