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Experimental Aging Research
An International Journal Devoted to the Scientific Study of the Aging Process
Volume 47, 2021 - Issue 4
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Brief Report

Can the RAVLT predict deterioration from MCI to dementia? Data from long term follow up

, , , , & ORCID Icon
Pages 347-356 | Received 22 Sep 2020, Accepted 01 Mar 2021, Published online: 11 Mar 2021
 

ABSTRACT

Objective

To assess whether the Rey Auditory Verbal Learning Test (RAVLT) could differentiate deterioration from Mild Cognitive Impairment (MCI) to dementia.

Methods

Twenty-six participants who were diagnosed with MCI performed the RAVLT and the Mini Mental State Examination (MMSE) at baseline and after nearly a decade (M = 8.8 years, SD = 3.16), in order to evaluate whether they progressed to dementia.

Results

Twelve participants [5 males, 7 females; age M = 63.7 (7.7)] kept their diagnoses of MCI; 14 participants [11 males, 3 females; age M = 75.0 (6.5)] converted to dementia. Both groups had similar MMSE scores at baseline [26.6 (0.6); and 26.6 (0.7) respectively]. Significant differences between dementia and MCI groups were found on most measures of the RAVLT at baseline: Immediate memory [p = .04], delayed recall [p = .003], total learning [p = .01], learning rate [p = .002], retrieval efficiency [p = .004], and false alarms [p = .004]. Thus, the RAVLT results were significantly worse at baseline in those who later converted. The results remain the same when controlling for age.

Conclusion

The results extend previous findings with follow-up of nearly a decade demonstrating that most of the RAVLT measures are sensitive to differentiate conversion from MCI to dementia.

Acknowledgments

Conflict of Interest: None of the authors declare competing financial interests.

Additional information

Funding

This work was not funded.

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