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Original Articles

Distributions of Runs Revisited

Pages 4663-4678 | Received 21 Aug 2012, Accepted 01 Apr 2013, Published online: 17 Nov 2015
 

Abstract

Distributions of runs have important applications in many fields, including biological sequence analysis. The generating function (GF) method provides a unified approach to tackle different run-related problems in multistate trials. By utilizing this method, various run-related distributions are derived in a systematic way for both conditional and unconditional models. The GF approach also naturally yields the asymptotic distributions. For all the distributions considered, the limiting distributions are Gaussian, with mean, variance, and covariance linear functions in the size of the system.

Mathematics Subject Classification:

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