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Original Articles

Bayesian prediction for two-stage sequential analysis in clinical trials

, &
Pages 9807-9816 | Received 16 Apr 2016, Accepted 28 Jul 2016, Published online: 20 Jun 2017
 

ABSTRACT

This article deals with a Bayesian predictive approach for two-stage sequential analyses in clinical trials, applied to both frequentist and Bayesian tests. We propose to make a predictive inference based on the notion of satisfaction index and the data accrued so far together with future data. The computations and the simulation results concern an inferential problem, related to the binomial model.

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