Abstract
For quadratic regression on the hypercube, G—efficiencies are often used in the selection process of an experimental design. To calculate a design's G—efficiency, it is necessary to maximize the prediction variance over the experimental design region. However, it is common to approximate a G—efficiency. This is achieved by calculating the prediction variances generated from a subset of points in the design space and taking the maximum to estimate the maximum prediction variance. This estimate is then applied to approximate the G—efficiency. In this paper, it will be shown that over the class of central composite designs (CCDs) on the hypercube. the prediction variance can be expressed in a closed-form. An exact value of the maximum prediction variance can then be determined by evaluating this closed-form expression over a finite subset of barycentric points. Tables of exact G—efficiencies will be presented. Design optimality criteria, quadratic regression on the hypercube, and the structures of the design matrix X, X'X, and (X'X)−1 for any CCD will be discussed.