A New Hemoglobin Variant: Hb Jiujiang [α18(A16)Gly→Cys, HBA2: c.55G>T]

Abstract

We have identified a new α chain hemoglobin (Hb) variant in a Chinese subject. Sequencing of the α-globin gene revealed a mutation in exon 1 at nucleotide 55, which results in the replacement of a glycine by cysteine at codon 18 [α18(A16)Gly→Cys, HBA2: c.55G>T] that we have named Hb Jiujiang for the region of origin of the proband.

Keywords:

• α-globin chain
• hemoglobin (Hb) variant
• hemoglobinopathy
• Hb Jiujiang

Disclosure statement

The authors report no conflicts of interest. The authors alone are responsible for the content and writing of this article.