Correction

This article refers to:

Fabrication of pH responsive hydrogel blends of chondroitin sulfate/pluronic F-127 for the controlled release of ketorolac: its characterization and acute oral toxicity study

Article title: Fabrication of pH responsive hydrogel blends of chondroitin sulfate/pluronic F-127 for the controlled release of ketorolac: its characterization and acute oral toxicity study

Authors: Naeem, S., Barkat, K., Shabbir, M., Khalid, I., Anjum, I., Shamshad, N., Mehmood, Y., Khan, D. H., Badshah, S. F., Syed, M. A., Afzal, S., & Abdullah, Z.

Journal: Drug Development and Industrial Pharmacy

Bibliometrics: Volume 48, Number 11, pages 611–622

DOI: https://doi.org/10.1080/03639045.2022.2150773

This article was first published online with incorrect Tables 3 and 4, which had methodology information and not the results data. Now both the Tables 3 and 4 have been replaced with the below Tables.

Table 3. Clinical observations of orally dispensed smart gels on rabbits.

Parameters Observed	C-group (Control)	T-group (administered with gel) 2g/kg
Indisposition signs	None	None
Body Weight (g)	Body Weight (g)	Body Weight (g)
Pre-treatment	1463.67 ± 108.15	1465.03 ± 116.74
1^st day	1464.19 ± 101.53	1467.00 ± 99.99
7^th day	1468.82 ± 107.18	1469.18 ± 115.47
14^th day	1470 ± 77.87	1469.99 ± 100.35
Water Utilization (ml)	Water Utilization (ml)	Water Utilization (ml)
Pre-treatment	201.33 ± 3.48	205.92 ± 3.95
1st day	196.11 ± 1.25	201 ± 0.8
7th day	194.66 ± 2.19	198.99 ± 1.63
14th day	196 ± 1.03	198.97 ± 2.19
Food Exhaustion (g)	Food Exhaustion (g)	Food Exhaustion (g)
Pre treatment	75.15 ± 1.35	78.10 ± 1.48
1st day	75.88 ± 2.47	79.12 ± 0.93
7th day	76.31 ± 1.84	76.24 ± 0.27
14th day	79.19 ± 3.70	80.11 ± 1.72
Dermal irritation	Nil	Nil
Ocular toxicity	Nil	Nil
Mortality	Nil	Nil

Table 4. Hematology, biochemical analysis and organ weight of Controlled and Test groups of Rabbits.

Haematology and biochemical analysis
Parameters Observed	C-group (Control)	T-group (administered with gel) 2g/kg
Hb (g/dl)	13.3 ± 0.2	14.1 ± 0.9
TLC mm^3	7900.0 ± 1003.0	5000.0 ± 963.0
Total RBCs (106 × mm^3)	6.23 ± 0.5	6.66 ± 0.8
Lymphocytes %	30.0 ± 2.4	37.0 ± 1.7
Monocytes %	03.0 ± 0.01	3.0 ± 0.0
MCH (pg)	27.3 ± 0.3	28.2 ± 0.6
MCV (µm^3)	79.7 ± 2.9	79.0 ± 2.0
MCHC%	32.6 ± 0.3	33.7 ± 1.2
Bilirubin Total (mg/dl)	0.10 ± 0.06	0.05 ± 0.02
Alkaline phosphate (U/L)	140.0 ± 3.7	145.0 ± 1.9
Urea (mg/dl)	38.0 ± 5.6	39.0 ± 8.8
Creatinine (mg/dl)	0.6 ± 0.1	0.8 ± 0.3
Total protein (G/dl)	6.5 ± 0.7	6.5 ± 1.0
Albumin (G/dl)	4.2 ± 0.3	4.0 ± 0.7
Triglycerides (mg/dl)	105.0 ± 1.0	110.0 ± 7.0
Cholesterol (mg/dl)	123.0 ± 6.0	106.0 ± 5.0
HDL-cholesterol (mg/dl)	48.0 ± 2.0	47.0 ± 3.0
LDL-cholesterol (mg/dl)	85.0 ± 5.0	89.0 ± 7.0
Hematocrit (PCV) %	43.4 ± 2.5	46.0 ± 3.1
Platelet count (mm^3)	318.0 ± 76.0	264.0 ± 42.0
A/G ratio (G/dl)	1.8 ± 0.1	1.6 ± 0.2
Organ Weight (gm) of Rabbits
Lung	3.93 ± 0.093	3.90 ± 0.050
Heart	4.27 ± 0.083	4.34 ± 0.059
Liver	41.08 ± 0.81	44.04 ± 1.03
Small intestine	108.1 ± 0.80	105.6 ± 1.04
Spleen	1.8 ± 0.06	2.0 ± 0.14
Kidneys	9.4 ± 1.05	9.1 ± 2.01