334
Views
21
CrossRef citations to date
0
Altmetric
ORIGINAL RESEARCH

Effect of Honey versus Sucrose on Appetite, Appetite-Regulating Hormones, and Postmeal Thermogenesis

, PhD, RD, , MS, , BS, , MS, , PhD, FMP, , MS & , PhD show all
Pages 482-493 | Received 09 Mar 2010, Accepted 12 Aug 2010, Published online: 08 Jun 2013
 

Abstract

Objective: Increased per capita consumption of sweeteners may be responsible in part for the rising prevalence of obesity in the United States. Recent studies suggest that consumption of honey is not associated with this same obesogenic effect and may have beneficial effects neuro on body weight. The purpose of this study was to evaluate whether the meal-induced responses of ghrelin and peptide YY3-36 (PYY3-36) and/or meal-induced thermogenesis differ following a honey- versus a sucrose-containing meal.

Methods: In a double-blind randomly assigned study, appetite hormones (ghrelin, PYY3-36, leptin) and glycemic and thermic responses were evaluated following isoglucidic ∼450 kcal honey- or sucrose-containing breakfasts in 14 healthy, nonobese women (22 ± 3 y). Blood samples and hunger ratings were obtained at baseline and every 30 minutes for 240 minutes following the meal. Meal-induced thermogenesis was measured by indirect calorimetry. Ad libitum food intake was evaluated from a free-choice meal following the test meal.

Results: Honey consumption delayed the postprandial ghrelin response (p  =  0.037), enhanced the total PYY (p  =  0.007) response, and blunted the glucose response (p  =  0.039) compared with consumption of the sucrose-containing meal. Meal-induced insulin response, hunger ratings, thermogenesis, and subsequent ad libitum food intake, however, did not differ (p > 0.10) between diet treatments.

Conclusions: Alterations in meal-induced responses of ghrelin and PYY3-36 but not meal-induced thermogenesis may be responsible in part for the potential “obesity protective” effect(s) of honey consumption. A blunted glycemic response may be beneficial for reducing glucose intolerance. Further research is required to determine if these findings hold true for obese individuals, for males, or with habitual consumption.

The authors want to thank research nurses Janell Marie Sherlock, RN, and Susan E. Lescznske, RN, and undergraduate students Nikki J. Peterson, Stephanie Hunter, and Megan McGuffey, for assistance with this study. We also thank Clif Bar & Company for donation of products used in the control diet and free-choice meals. Our gratitude is extended to the volunteers for their participation in this very demanding research study. This work was supported by USDAAMS44700.

Log in via your institution

Log in to Taylor & Francis Online

PDF download + Online access

  • 48 hours access to article PDF & online version
  • Article PDF can be downloaded
  • Article PDF can be printed
USD 53.00 Add to cart

Issue Purchase

  • 30 days online access to complete issue
  • Article PDFs can be downloaded
  • Article PDFs can be printed
USD 139.00 Add to cart

* Local tax will be added as applicable

Related Research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.