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Short Communication

Antimicrobial Activity of Gallic Acid-Grafted-Chitosan Against Fish Pathogens

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Pages 163-171 | Received 17 Dec 2014, Accepted 10 Feb 2015, Published online: 08 Apr 2015
 

GRAPHICAL ABSTRACT

The objective of this study is to evaluate the antibacterial activity of the gallic acid-grafted-chitosan (GA-g-chitosan) against important fish pathogens. The antibacterial assay revealed that the GA-g-chitosan was most active against Streptococcus parauberis 12046 but had relatively weak activity against Streptococcus iniae and Vibrio anguillarum. The minimum inhibitory concentrations (MICs) of the GA-g-chitosan against five S. parauberis strains were 96 to 128 μg/mL. The cell integrity and microscopic observation indicated that the GA-g-chitosan exerted the antibacterial activity against S. parauberis through a membrane damage mechanism.

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