Radiotherapy for Orbital Pseudotumor: The University of Florida Experience

Abstract

Background: To evaluate outcomes after definitive radiotherapy for orbital pseudotumor. Methods: We reviewed adult patients treated between 1971 and 2012. Results: 20 patients with 8.0-year median follow-up were analyzed. Symptoms improved in 75% of patients: 40% showed a complete response, 35% partial response, and 20% had stable disease. The disease progressed in 1 and recurred in 8 patients. Local control rates were 63% and 53% at 5 and 10 years, respectively. The most common toxicities were cataracts (10%) and dry eye (10%). Conclusions: Radiotherapy for orbital pseudotumor is well-tolerated and results in long-term control in most patients, with local control in over half.

Keywords:

• Radiation oncology
• Radiotherapy
• Orbital pseudotumor
• Outcomes
• retrospective review

Acknowledgments

The authors would like to thank Jessica Kirwan and Christopher Stich for excellent editorial assistance.

Disclosure statement

We have read and understood Cancer Investigation’s policy on disclosing conflicts of interest and declare that we have none.