A Systematic Review of the Treatment Outcomes among Prostate Cancer Patients in Africa

Abstract

Prostate cancer (PCa) is associated with a significant public health burden in Africa. This systematic review aimed to assess treatment outcomes among PCa patients in Africa. A systematic search of the literature was conducted from 1 December 2021 to 31 March 2022 to identify relevant published studies. PubMed, EMBASE, CINAHL, and Google Scholar databases were used. Twenty-four studies met the inclusion criteria, and the mean age was 68 years. Localized and locally advanced diseases had relatively higher overall survival than metastatic diseases. In metastatic disease, the mean overall five-year survival was 42% which is shorter than the Asian population (61.9%).

Keywords:

• Treatment outcomes
• prostate cancer
• systematic review
• Africa

Acknowledgments

The authors acknowledge the United States International University-Africa for their internet support for this systematic review.

Author contributions

AD, ANM, and PMN conducted the literature search, screening, methodological quality assessment, and data analysis; all the authors contributed to the write up of the review manuscript; all the authors have agreed on the journal to which the article will be submitted, gave final approval of the version to be published, and agree to be accountable for all aspects of the work.

Disclosure statement

No potential conflict of interest was reported by the author(s).

Data availability statement

The data sets used during the current review are available from the corresponding author on a reasonable request.