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ABSTRACT
This paper reviews the results obtained by studying the sorption of physiologically active substances (PAS) of different types such as, amino acids, nucleotides and melanoidins on ion exchangers and non-ionogenic sorbents. The review is mainly focused upon die mechanisms of interaction of PAS molecules in the sorbent phase. The contribution of ion-ionic, ion-molecular and intermolecular interactions to the overall sorption effect is discussed. The results of studying ion-exchange isothermal supersaturation of amino acid solutions on anion exchangers are reported and discussed. The mechanisms of aging of ion-exchange materials in the course of recovery of PAS from fermentation broths and hydrolysates are proposed.