Manufacture of Standardized Dried Extracts from Medicinal Brazilian Plants

ABSTRACT

This article presents a brief review of the research conducted at Laboratory of Pharmaceutical Processes of the Faculty of Pharmaceutical Sciences of Ribeirão Preto/São Paulo University, aiming to obtain standardized dried extracts from medicinal Brazilian plants. The spray and spouted-bed dryer performance and physicochemical product properties during the drying of hydro-alcoholic extracts of three plants used in the Brazilian traditional medicine, namely, Passiflora alata, Bauhinia forficata, and Maytenus ilicifolia, are evaluated comparatively.

Keywords:

• Drying
• Spray dryer
• Spouted bed
• Herbal extract
• Medicinal plants

ACKNOWLEDGMENTS

We express our gratitude to FAPESP for the financial support (Proc. 03/08317-1, 04/07748-1, and 01/10140-7).

Notes

∗H₀: static bed height; T_gi: inlet gas temperature; γ: conical base angle; W_s/W_max: mass flow rate of extract relative to evaporation capacity of the dryer; Q/Q_jm: spouting gas flow rate relative to gas flow at minimum spouting.

∗Total flavonoids: B. forficata and P. alata; Total tannins: M. ilicifolia.

∗Total flavonoids: B. forficata and P.alata; Total tannins: M. ilicifolia (wet basis).

∗Concentration of the chemical marker.

^#Thermal degradation of the active compounds.

∗Ac = accumulation rate.