Calculating degree based multiplicative topological indices of Hyaluronic Acid-Paclitaxel conjugates’ molecular structure in cancer treatment

Abstract

A large number of medical experiments have confirmed that the features of drugs have a close correlation with their molecular structure. Drug properties can be obtained by studying the molecular structure of corresponding drugs. The calculation of the topological index of a drug structure enables scientists to have a better understanding of the physical chemistry and biological characteristics of drugs. In this paper, we focus on Hyaluronic Acid-Paclitaxel conjugates which are widely used in the manufacture of anticancer drugs. Several multiplicative topological indices of this molecular structure are determined by using of the edge-partition method.

Communicated by Ramaswamy H. Sarma

Keywords:

• Multiplicative sum connectivity index
• multiplicative randić index
• cancer treatment

AMS subject classification:

• 05C50

Disclosure statement

No potential conflict of interest was reported by the author(s).

Additional information

Funding

This work has been financially supported by Azarbaijan Shahid Madani University under the grant number ASMU/6/98. The second author is supported by the National Key R & D Program of China (Grant No. 2019YFA0706402).