A review on expression and regulatory mechanisms of miR-337-3p in cancer

Abstract

A group of diseases generally referred to as cancer represents a serious threat to people’s health all over the world and has a significant negative influence on every aspect of the lives of patients. The development of cancer is influenced by several environmental, genetic, and epigenetic factors. MicroRNAs (miRNAs), a class of non-coding RNAs, can alter the expression of genes involved in cell proliferation, migration, metastasis, and apoptosis, lead to the pathogenesis of cancer. Additionally, several effectors modify miRNAs directly, including methylation, circular RNAs, and long non-coding RNAs (lncRNAs). In this review, we have explained the role of mir-337-3p in the pathways related to the pathogenesis of different cancers. Studying the functional role of miR-337-3p is necessary for detecting novel molecules as tumor markers and discovering novel targets for cancer treatment.

Communicated by Ramaswamy H. Sarma

Keywords:

• MicroRNA
• cancer
• miR-337-3p
• non-coding RNAs

Author contributions

All authors contributed to the study’s conception and design. Data collection was performed by Mehran Dehghanian and Ghafour Yarahmadi. The first draft of the manuscript was written by Mehran Dehghanian, and all authors commented on previous versions of the manuscript. All authors read and approved the final manuscript.

Consent form

This research does not involve human subjects.

Disclosure statement

The authors have no relevant financial or non-financial interests to disclose.

Ethical approval

This is a review article.

Additional information

Funding

The authors declare that no funds, grants, or other support were received during the preparation of this manuscript.