The Effects of Intravitreal Ophthalmic Medications on Intraocular Pressure

Abstract

Ophthalmic medications are often given as intravitreal injection. Antimicrobials, antivirals, corticosteroids and anti- vascular endothelial growth factor agents are the main classes which can be administered through intravitreal injections. Possible complications of intravitreal injection include intraocular pressure changes, especially intraocular pressure elevations. This review discusses both injection-related intraocular pressure elevations which can occur immediately after injection of any kind of medication and drug specific-related intraocular pressure changes which may be detected days or even months after the injection.

Keywords:

• intraocular pressure
• Injections
• Vitreous body
• pegaptanib
• ranibizumab
• bevacizumab
• Triamcinolone acetonide
• Antiviral Agents
• Antibiotics Macugen
• Lucentis
• Avastin