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Seminars in Ophthalmology Volume 36, 2021 - Issue 4: Massachusetts Eye and Ear Infirmary
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Review

Potential of Application of Iron Chelating Agents in Ophthalmic Diseases

Alireza Ghaffarieha Ophthalmology, Cornea, External Disease & Refractive Surgery Fellow, Massachusetts Eye and Ear Infirmary, Harvard University, USACorrespondence[email protected]
&
Joseph B. Ciolinob Ophthalmology, Associate Professor of Ophthalmology, Harvard Medical School Mass. Eye and Ear/Schepens Eye Research Institute, USA
Pages 157-161 | Received 11 Jan 2021, Accepted 19 Jan 2021, Published online: 23 Feb 2021
 
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ABSTRACT

The investigations discussed in this review indicate that iron may exacerbate different eye diseases. Therefore, it is plausible that reducing cellular or body iron stores could influence disease pathogenesis, so it is logical to consider the iron chelators’ potential protective role in the various ophthalmic diseases in the form of topical eye drops or slow releasing injectable compounds as an adjuvant treatment.

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