Two-Year Outcomes of Ultrasound Cyclo Plasty as a First Procedure in Glaucoma

ABSTRACT

Purpose

To evaluate the 2-year outcomes of ultrasound cyclo plasty (UCP) as a first procedure in glaucoma.

Methods

This retrospective cohort study included patients with uncontrolled glaucoma who underwent UCP as an initial glaucoma procedure. The main outcome measures were intraocular pressure (IOP), the number of antiglaucoma medications, visual acuity, and the presence of vision-threatening complications. Surgical outcomes of each eye were classified as either complete success, qualified success, or failure based on the main outcome measures. Differences in IOP control and success rates were compared in eyes with primary open-angle glaucoma (POAG) and primary angle-closure glaucoma (PACG).

Results

We included 98 eyes of 88 patients in the study. The mean follow-up period was 27.25 ± 10.1 months. At 12 and 24 months, mean IOP decreased significantly from 23.16 ± 6.4 mmHg to 16.57 ± 6.0 mmHg and 16.18 ± 5.2 mmHg, respectively, and the number of antiglaucoma medications decreased from 3.27 ± 0.9 to 1.86 ± 1.4 and 1.70 ± 1.7, respectively (p < .01 for all). There were no changes in visual acuity throughout the follow-up compared with preoperative levels. The cumulative probabilities of success were 64.3% (±4.8) [78.9% (±9.4) complete success, and 72.9% (±6.4) qualified success], and 42.9% (±5.0) [52.6% (±11.5) complete success, and 56.3% (±7.2) qualified success] at 12 and 24 months, respectively. The most common complications were cataract development/progression, anterior chamber inflammation, and macular edema. There were no significant differences in IOP, number of antiglaucoma medications, or survival rates between POAG and PACG groups.

Conclusions

UCP can be used as an initial glaucoma procedure for reducing IOP and the number of antiglaucoma medications and offers comparable outcomes in POAG and PACG.

KEYWORDS:

• Ciliary body
• Cyclocoagulation
• Glaucoma
• High-intensity focused ultrasound
• Intraocular pressure
• Ultrasound cyclo plasty

DISCLOSURE STATEMENT

No potential conflict of interest was reported by the author(s).

COMPLIANCE WITH ETHICS GUIDELINES

The study was approved by the institutional review board (E-22-6738) of King Saud University, and all procedures adhered to the tenets of the Declaration of Helsinki.

AUTHOR CONTRIBUTIONS

All authors contributed to the study conception, design, and data collection. Faisal A. Almobarak wrote the initial draft and undertook the analysis. All authors reviewed the draft and approved the final manuscript.

DATA AVAILABILITY STATEMENT

All data are available from the corresponding author upon request.

Additional information

Funding

The author(s) reported there is no funding associated with the work featured in this article.