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Original Articles

Co-rumination and Immune Inflammatory Response in Healthy Young Adults: Associations with Interleukin-6 and C-Reactive Protein

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Pages 152-161 | Published online: 18 Dec 2017
 

Abstract

A rich literature exists reinforcing the notion that both perceived and received social support has stress ameliorating and protective benefits both psychologically and physiologically. However, recent literature suggests that excessive dyadic negative problem talk about an issue, a phenomenon labeled co-rumination, may reverse much of the beneficial effects of social support. Healthy young adults participated in a laboratory research study exploring the associations between co-rumination and immune system inflammatory response. Partial correlations indicated a positive association between co-rumination and C-reactive protein and a negative association between co-rumination and interleukin-6 after controlling for stress, anxiety, and temperature. Discussion focuses on the means by which co-rumination may lead to negative health outcomes.

Acknowledgments

The authors would like to thank our research assistants for their exemplary work with the data collection on this project, Angeles Oviedo and Mari Katsura from Santa Clara University and Erin Rolaff and Kristin English from Christopher Newport University.

Notes

[1] Although certain test cartridge lots were a part of a Class 2 recall of the Cholestech CRP kit (recall #Z11782013), these data were collected prior to that recall, and the cartridges used in this study were not included.

[2] CRP (West n = 54, M = 1.51, SD = 2.08; East n = 30, M = 2.09, SD = 2.83), t(82) = −1.09, p = .28, d = .23; IL-6 (West n = 45, M = 7.15, SD = 8.61, East n = 18, M = 7.10, SD = 6.40), t(61) = .02, p = .96, d = .007; and co-rumination (West n = 65, M = 2.65, SD = .82, East n = 36, M = 2.98, SD = .81), t(99) = −1.93, p = .06, d = .40.

Additional information

Funding

This research was supported by both a Thomas Terry Research Grant and the Faculty-Student Research Assistant Program from Santa Clara University.

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