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Research Article

Mucosally associated bacterial flora of the human colon: quantitative and species specific differences between normal and inflamed colonic biopsies

Pages 169-174 | Published online: 11 Jul 2009
 

Abstract

This study quantified and characterised changes to a species level for aerobic and anaerobic bacteria from colonic biopsies of acute ulcerative colitis (UC) comparing them with that of a normal control group. Fresh endoscopic biopsies of the recto-sigmoid region were obtained during flexible sigmoidoscopy from 10 patients suffering an acute attack of UC and a similar number of healthy controls. Quantitative estimation was carried out on selective media for total aerobic, anaerobic,